valinomycin

valinomycin
A potassium ionophore antibiotic, produced by Streptomyces fulvissimus. Composed of 3 molecules (L-valine, D -a- hydroxyisovaleric acid, L-lactic acid) linked alternately to form a 36-membered ring, that folds to make a cage shaped like a tennis-ball seam. This wraps specifically around potassium ions, presenting them with a hydrophilic interior, and a lipid bilayer with a hydrophobic exterior. Potassium is thus free to diffuse through the lipid bilayer. Highly ion specific, valinomycin is used in ion-selective electrodes.

Dictionary of molecular biology. 2004.

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  • valinomycin — valinomycin. См. валиномицин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • valinomycin — [val΄ə nō mī′sin] n. [< VALINE + MYCIN] an antibiotic polypeptide isolated from soil bacteria, that promotes the movement of potassium ions in cells …   English World dictionary

  • Valinomycin — Strukturformel Allgemeines Name Valinomycin Andere Namen …   Deutsch Wikipedia

  • Valinomycin — chembox new ImageFile = Valinomycin.svg ImageSize = IUPACName = OtherNames = Formula = C54H90N6O18 Section1 = Chembox Identifiers Abbreviations = CASNo = 2001 95 8 EINECS = PubChem = SMILES = InChI = RTECS = MeSHName = ChEBI = KEGG = ATCCode =… …   Wikipedia

  • valinomycin — /val euh noh muy sin/, n. Pharm. a cyclic, peptide antibiotic, C54H90N6O18, produced by the bacterium Streptomyces fulvissimus; used experimentally to transport potassium across membranes. [ < G Valinomycin (1955); see VALINE, O , MYCIN] * * * …   Universalium

  • valinomycin — noun An antibiotic, having a cyclic oligopeptide structure, derived from the actinomycete Streptomyces fulvissimus …   Wiktionary

  • valinomycin — Cyclododecadepsipeptides ionophore antibiotic derived from Streptomyces fulvissius; a 36 membered ring structure consisting of 3 mol each of l valine, d α hydroxyisovaleric acid, d valine, and l lactic acid linked alternately. The material is… …   Medical dictionary

  • valinomycin — val·in·o·my·cin …   English syllables

  • valinomycin — ˌvalə̇(ˌ)nōˈmīsən noun ( s) Etymology: valine + o + mycin : an antibiotic C54H90N6O18 produced by a bacterium of the genus Streptomyces (S. fulvissimus) …   Useful english dictionary

  • валиномицин — valinomycin валиномицин. Пептидный антибиотик, ионофор <ionophores>, осуществляющий перенос ионов калия и рубидия через клеточные мембраны. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А.,… …   Молекулярная биология и генетика. Толковый словарь.

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